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The results show that in about half of the cases where researchers were able to closely mimic the design of the corresponding RCT using RWD, the RWE study came to a similar conclusion as the analogous RCT. In many cases where RWE and RCTs did not come to a similar conclusion, the RCT design itself did not align with real-world clinical practice, creating a challenge for emulation of the trial using RWD. In these instances, RWE and RCTs may both be reaching meaningful conclusions, but to subtly different research questions.
My Happiness vs The Pandemic. In Spreadsheets.
I have been tracking my mood every day throughout this pandemic. I use an app that I released myself called Changes. It lets me write a little diary entry and rate my mood and add hashtags.
I’ll analyse this data and see what actually happened. I’ll be using Google Sheets to help you try the same with your data in future.
"Asking Too Much?": Randomized N-of-1 Trial Exploring Patient Preferences and Measurement Reactivity to Frequent Use of Remote Multidimensional Pai... - PubMed - NCBI
Once-a-day pain reporting provides rich contextual information. Although patients were less adherent to this preferred sampling strategy, once-a-day reporting still provides more frequent assessment opportunities compared with other less intense or overburdensome schedules.
A Randomized Clinical Trial of n-of-1 Trials—Tribulations of a Trial | Research, Methods, Statistics | JAMA Internal Medicine | JAMA Network
Given the lack of evidence in their favor and their inconvenience for patients and physicians, the burden of proof now firmly rests with their proponents. With everything said, we empathize with our colleagues, but for now this may represent another instance of a beautiful idea being vanquished by cruel and ugly evidence.
Doctors Prescribe More of a Drug If They Receive Money from a Pharma Company Tied to It — ProPublica
On average, across all drugs, providers who received payments specifically tied to a drug prescribed it 58% more than providers who did not receive payments.
Cognitive errors in medicine: The common errors - First10EM
This list represents the cognitive biases that are most often described in the context of medical errors, but there are many other cognitive biases that affect our daily lives. For example, I particularly like the IKEA effect: our tendency to disproportionately value objects we had a hand in putting together, regardless of end result.
Real-time personalization and recommendation | Amazon Personalize | AWS
Delivering personalization to individuals at scale requires a combination of the right data and the right technology. The algorithms used by Amazon Personalize are designed to overcome common problems when creating custom recommendations – such as new users with no data, popularity biases, and evolving intent of users – to deliver high-quality recommendations that respond to specific needs, preferences, and behavior of your users.
The medium is the medicine: a novel history
Before 1900, “many people thought of medicine as an inferior profession, or at least a career with inferior prospects,” according to Starr. The average American doctor earned less than “an ordinary mechanic,” riding miles each day on horseback to see just a handful of patients.
The status of doctors changed dramatically in the first decade of the 20th century, when cars, telephones and urbanization made practicing medicine more efficient and therefore more lucrative.