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Adam Tooze, Crisis Historian, Has Some Bad News for Us - The AtlanticRussia’s foreign-exchange reserves, for instance. One Tooze post examined how accumulating those reserves helped Vladimir Putin turn the country into a “strategic petrostate” bold enough to invade Ukraine and capable of countering Western powers. About 150,000 people, including some in the German chancellor’s office, read the essay. “I thought, Wow, this is worthwhile,” Tooze told me. “For somebody who comes out of an academic publishing background, where you’re lucky if 1,000 people read what you write, the numbers tick up so fast.” On Substack, his output also proved financially rewarding: “For anyone on a regular, white-collar, academic-type salary, it’s transformative.”
Investors have been snubbing the microbiome. That may be changingThe field needed to find some basic tools before it had a chance of developing a drug successfully, she said, like better biomarkers to determine how and where a drug was working. For example, in one paper, Synlogic scientists showed that their drug was working by tracking an isotope markers through the bacteria’s metabolic pathway and by measuring levels of a chemical produced by their bacterial “drug,” SYNB1618. “One of the challenges that microbiome companies face is that you can tell what goes in the top end, you can tell what comes out the bottom end, but you can’t tell what happens in the middle,” Brennan said during a presentation earlier this month. “There’s a lot of groundwork that’s required. Papers don’t make good drugs,” she said in an interview afterward.
Munger: pick your fightsIf you want to be the best tennis player in the world, you may start out trying and soon find out that it's hopeless—that other people blow right by you. However, if you want to become the best plumbing contractor in Bemidji, that is probably doable by two-thirds of you. It takes a will. It takes the intelligence. But after a while, you'd gradually know all about the plumbing business in Bemidji and master the art. That is an attainable objective, given enough discipline. And people who could never win a chess tournament or stand in center court in a respectable tennis tournament can rise quite high in life by slowly developing a circle of competence—which results partly from what they were born with and partly from what they slowly develop through work.
Art Envy is the easiest way to create, update and share your art online. So you can have more time to do what you love most, practice your art.
Like their brick-and-mortar brethren that have long dealt with stiff competition, startup subscription sites are homing in on consumers' ever narrowing interests and the seemingly universal love of all things homemade.