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Researchers identify potential new means of slowing neurodegenerative diseases -- ScienceDaily

The normal function of Hsp90 is to support healthy cellular processes, but oxidation can have profound effects on the three-dimensional structure of a protein such as Hsp90, altering its function, Franco said. "By understanding the ways that oxidation modifies the Hsp90 structure, and how the oxidized protein works in the cells, we can look for drugs that bind to the modified structure of Hsp90 and stop its toxic function without affecting the activity of normal Hsp90 in healthy tissues," she said. "That means such drugs should have minimal to no side effects."

#neurons #Alzheimers #hsp90 - sciencedaily.com

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