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Anticoagulants reduce the number of brain metastases in mice -- ScienceDaily

It was already known from observational studies that antithrombotic drugs that inhibit blood clotting can have a favorable effect on the prognosis of certain cancers. It is possible that these agents influence metastasis. Winkler and his colleagues have now investigated in mice whether this also applies to brain metastases and, if so, how blood clotting and metastasis are linked. This study was made possible by a special microscopic technique (in vivo multiphoton laser-scanning microscopy) that allows the researchers to look deep into brain tissue and track individual cancer cells.

Study shows anticoagulation therapy beneficial for COVID-19 patients

Of the patients analysed, 900 (20.5 percent) received a full-treatment dose of anticoagulants. Another 1,959 patients (44.6 percent) received a lower, prophylactic dose of anticoagulants and 1,530 (34.5 percent) were not given blood thinners. There was a strong association between blood thinners and reduced likelihood of in-hospital deaths: both therapeutic and prophylactic doses of anticoagulants reduced mortality by roughly 50 percent compared to patients on no blood thinners.