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Doctor quits Brigham to speak for pay - The Boston Globe’’There are physicians earning so much money [from drug makers] that they would give up their jobs,’’ said Dr. Steven Nissen, head of cardiovascular medicine at the Cleveland Clinic Foundation. “It’s a shocking story. Normally you’d give up the [pharmaceutical company] honoraria.’’
Research Center Tied to Drug Company - The New York TimesA June 2002 e-mail message to Dr. Biederman from Dr. Gahan Pandina, a Johnson & Johnson executive, included a brief abstract of a study of Risperdal in children with disruptive behavior disorder. The message said the study was intended to be presented at the 2002 annual meeting of the American Academy of Child and Adolescent Psychiatry. “We have generated a review abstract,” Dr. Pandina wrote, “but I must review this longer abstract before passing this along.” One problem with the study, Dr. Pandina wrote, is that the children given placebos and those given Risperdal both improved significantly. “So, if you could,” Dr. Pandina added, “please give some thought to how to handle this issue if it occurs.” The draft abstract that Dr. Pandina put in the e-mail message, however, stated that only the children given Risperdal improved, while those given placebos did not. Dr. Pandina asked Dr. Biederman to sign a form listing himself as the author so the company could present the study to the conference, according to the message. “I will review this morning,” responded Dr. Biederman, according to the documents. “I will be happy to sign the forms if you could kindly send them to me.” The documents do not make clear whether he approved the final summary of the brief abstract in similar form or asked to read the longer report on the study.
Research Center Tied to Drug Company - The New York TimesA February 2002 e-mail message from Georges Gharabawi, a Johnson & Johnson executive, said Dr. Biederman approached the company “multiple times to propose the creation” of the center. “The rationale of this center,” the message stated, “is to generate and disseminate data supporting the use of risperidone in” children and adolescents.
Research Center Tied to Drug Company - The New York TimesIn a November 1999 e-mail message, John Bruins, a Johnson & Johnson marketing executive, begs his supervisors to approve a $3,000 check to Dr. Biederman as payment for a lecture he gave at the University of Connecticut. “Dr. Biederman is not someone to jerk around,” Mr. Bruins wrote. “He is a very proud national figure in child psych and has a very short fuse.”
Research Center Tied to Drug Company - The New York TimesBut e-mail messages and internal documents from Johnson & Johnson made public in a court filing reveal that Dr. Biederman pushed the company to finance a research center at Massachusetts General Hospital, in Boston, with a goal to “move forward the commercial goals of J.& J.” The documents also show that the company prepared a draft summary of a study that Dr. Biederman, of Harvard, was said to have written.
Research Center Tied to Drug Company - The New York Timestors. In a November 1999 e-mail message, John Bruins, a Johnson & Johnson marketing executive, begs his supervisors to approve a $3,000 check to Dr. Biederman as payment for a lecture he gave at the University of Connecticut. “Dr. Biederman is not someone to jerk around,” Mr. Bruins wrote. “He is a very proud national figure in child psych and has a very short fuse.” Mr. Bruins wrote that Dr. Biederman was furious after Johnson & Johnson rejected a request that Dr. Biederman had made for a $280,000 research grant. “I have never seen someone so angry,” Mr. Bruins wrote. “Since that time, our business became non-existant (sic) within his area of control.” Mr. Bruins concluded that unless Dr. Biederman received a check soon, “I am truly afraid of the consequences.”
Biederman designed studies to deliver results desired by drug makersOne set of slides in the documents referred to “Key Projects for 2004” and listed a planned trial to compare Risperdal, also known as risperidone, with competitors in managing pediatric bipolar disorder. The trial “will clarify the competitive advantages of risperidone vs. other neuroleptics,” the slide stated. All of the slides were prepared by Dr. Biederman, according to his sworn statement.
Why is exercise hard? | Harvard MagazineThis tension between activity and rest, he says, plays out in human physiological and anatomical systems that “evolved to require stimuli from physical activity to adjust capacity to demand.” Muscles become bigger and more powerful with use, for example. With disuse, they atrophy. Bone deposition and repair mechanisms likewise require the presence of mechanical stimulation, such as running. The absence of such stimuli can eventually lead to a risk of osteoporosis. “In the circulatory system,” Lieberman continues, “vigorous activity stimulates expansion of peripheral circulation,” improves the heart’s ability to pump blood, “and increases arterial elasticity.” Without exercise, arteries stiffen, the heart pumps less blood, and metabolism slows. All of this “downregulation” of biological systems evolved to conserve energy whenever possible.
JFK's Very Revealing Harvard Application EssayThe reasons that I have for wishing to go to Harvard are several. I feel that Harvard can give me a better background and a better liberal education than any other university. I have always wanted to go there, as I have felt that it is not just another college, but is a university with something definite to offer. Then too, I would like to go to the same college as my father. To be a "Harvard man" is an enviable distinction, and one that I sincerely hope I shall attain. April 23, 1935 John F. Kennedy
Key to great "Harvard sucks" prank was failure and new recruitsUnfortunately, many of their original collaborators from the year before were discouraged by the original plan's untimely demise. According to Kai, a new group of Yale students was recruited for the prank at Harvard Stadium. "Most of the people who helped us our junior year didn't want to help senior year, after seeing the failure," Kai told Business Insider. "So it became a mix of close friends and freshmen, who hadn't seen the failed plan."
I am mad that a woman of her stature could perform such a criminal act of dishonesty—at Harvard, of all places.