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Scientists see inner workings of enzyme telomerase, which plays key roles in aging, cancer: Detailed view of its core may lead to development of targeted drugs -- ScienceDaily
"We're now seeing not just the face of the clock, we're seeing how the components inside interact to make it work," said Juli Feigon, a professor of chemistry and biochemistry in the UCLA College and a senior author of the study. "At each step, we zoom in closer and see more and more details, and can now begin to deduce not just what the enzyme looks like, but also how it functions. Knowing that may lead to the development of new drugs that target specific parts of the enzyme."
Human cognitive map scales according to surroundings -- ScienceDaily
Humans rescale their internal coordinate system according to the size of each new environment. This flexibility differs from rodents' rigid map that has a constant grid scale and empowers humans to navigate diverse places.
When seeking navigational cues in any given location, humans automatically align their internal compass with the corners and shape of the space. In contrast, rodents do so relative to the walls of the environment through physical exploration.
The nature of the coordinate system differs between humans and rodents -- Cartesian and hexagonal respectively.
The findings illuminate the fabric of the human memory and spatial navigation, which are vulnerable to disease and deterioration. Deeper knowledge of these neuronal mechanisms can inform the development of techniques to prolong the health of this part of the brain and combat diseases such as Alzheimer's.
Digital giants get bigger at the expense of the small blog sites
So the result of the 2014 new-money surge is that the world of online publishing has become bifurcated. Either you aspire to become a “platform”, or you simply join up with somebody else’s. (Take your choice: WordPress, Tumblr, Medium, YouTube or, of course, Facebook.) The small but self-sustaining bloggy site is a thing of the past: if you’re not getting 20-30 million unique visitors every month, and don’t aspire to such heights, then you’re basically an economic irrelevance. Advertisers won’t touch you, you won’t make any money, and your remaining visitors will inexorably leach away as they move from their desktops to their phones.