Pullquote: @hc

Recent quotes:

Investors have been snubbing the microbiome. That may be changing

The field needed to find some basic tools before it had a chance of developing a drug successfully, she said, like better biomarkers to determine how and where a drug was working. For example, in one paper, Synlogic scientists showed that their drug was working by tracking an isotope markers through the bacteria’s metabolic pathway and by measuring levels of a chemical produced by their bacterial “drug,” SYNB1618. “One of the challenges that microbiome companies face is that you can tell what goes in the top end, you can tell what comes out the bottom end, but you can’t tell what happens in the middle,” Brennan said during a presentation earlier this month. “There’s a lot of groundwork that’s required. Papers don’t make good drugs,” she said in an interview afterward.

#microbiome #diagnostics #nanoniche #pathways - statnews.com

All

consulting x2 DOGE x1 USAUSA x131 chapel-hill x2 food x91 VC x21 IVF x1 medicalindustrialcomplex x309 financialization x1 GFC x2 inflation x29 banking x2 volker x1 80s x4 interst-rates x14 economics x38 neoliberalism x1 beehiiv x1 newsletters x5 substack x2 innovation x136 models x7 theory x21 trial-and-error x9 more-moore x19 n-of-1 x26 precision-medicine x3 macular-degeneration x2 sleep-apnea x12 insurance x11 nicotine x9 pot x20 christmas x1 narratives x121 sixties x3 traditions x1 predatory x1 wall-street x20 medicare x1 diagnostics x9 doctors x52 overdiagnosis x3 etf x2 predictions x23 stocks x5 LAD x2 RYR x1 aging x72 Alzheimers x28 dementia x8 muscles x12 strength x6 Hungary x88 poetry x19 svaby x1 affiliate x1 amazon x54 influencers x3 lawyers x5 social-media x73 style-substance x2 CCRC x1 retirement x2 asheville x1 hospitals x5 nurse-practioners x1 homeless x2 home x15 journalism x58 history x97 meaning x7 sexism x53 adbiblio x9 LLM x8 publishing x98 ChatGPT x4 prediction x115 copyright x1 games x32 nytimes x44 AI x55 docbots x17 401k x1 upcoding x1 dopamine x51 exercise x181 parkinsons x11 antidepressants x30 cognition x19 hiit x6 racery x89 2024 x3 government x3 musk x2 trump x74 media x36 anti-semitism x11 ethics x2 medicine x45 research x8 orban x8 NATO x2 cult x8 rumors x1 stress x33 connectome x37 networks x70 knowledge-workers x11 pullquote x37 reading x32 success x8 immune-system x39 keto x10 multiple-sclerosis x5 crime x2 england x14 london x14 cycles x1 progress x2 nyc x47 race x45 indy x2 marketing x49 religion x28 instagram x4 politics x72 fascism x1 evernote x1 quizlab x2 stenosis x8 trodusquemine x1 crypto x5 markets x22 nature x23 North-Carolina x33 cholesterol x6 counter-intuitive x5 archeology x7 river x1 GOP x17 military x1 test x2 carbs x16 LDL x2 churn x1 longevity x9 rapamycin x1 disruption x26 graphene x1 coronavirus x93 FDA x18 pharma x66 statins x8 diabetes x82 metformin x5 long-covid x3 adderall x6 psychiatry x61 psychosis x58 apnea x9 diamox x5 sulthiame x2 cytokines x7 epilepsy x1 cancer x37 corruption x3 wwb x16 LPA x1 baking-soda x2 running x95 indexfunds x1 valuation x2 REM x8 sleep x93 socializing x17 abortion x1 citizen-medicine x4 DIY x8 art x52 writing x68 france x30 Hegel x1 intellectual-history x4 myelin x6 experiments x7 managing x250 MBA x6 marriage x51 devices x1 hardware x1 harvard x12 McLuhan x6 software x16 heat x4 tales x1 real-estate x21 rental x1 nationalism x9 tiktok x1 projection x3 statistics x10 loneliness x7 free-speech x2 Walz x1 angioplasty x1 stent x1 blogads x20 fasting x13 fat x20 inflamation x58 leptin x2 flexibility x3 inspo x1 literature x23 tech x12 silicon-valley x13 lipids x1 burningman x1 pollution x5 ADHD x73 distraction x6 europe x47 germany x1 recursion x1 travel x6 hippocampus x40 memory x105 lymphangions x1 cycling x18 right-on-red x1 haidt x3 suicide x7 teens x15 moral-panic x4 academia x76 allergy x20 anaphylaxis x1 disclosure x2 brain x161 concussion x3 CTE x4 alcohol x51 children x22 vance x3 dengue x1 verbosity x1 words x38 racism x33 digitalhealthcommunities x2 reddit x6 conferences x1 vaccines x9 populism x3 weightlifting x6 culture x11 tribes x1 Russia x40 USSR x37 christian x1 constitution x1 melatonin x7 gut x17 micro-biome x22 cannabinoids x6 nami x2 gaza x1 steps x1 heart x32 paleotherapy x126 multiomic x1 epistemology x2 goog x26 pressflex x2 search x3 health x206 Twitter x27 relationship x4 synchronize x205 the-triangle x2 science x26 ketamine x3 megalomania x1 psychotropics x5 psychology x108 depression x210 neurogenesis x2 misdiagnosis x7 amygdala x16 music x83 deep-brain-stimulation x6 DNA x79 smoking x11 beatles x6 viral x12 disability x1 hoosiers x1 medicaid x2 gutenberg x1 print x6 vegan x3 communism x18 video x4 neuro-plasticity x1 vitamin-d x6 TBI x10 pioneers x1 SaaS x2 Obit x5 real-politik x1 RIP x34 bonds x13 cgm x1 glucose x9 debt x4 thefed x2 liver x3 peter-principle x1 non-protein-amino-acids x1 cities x29 doom-loop x2 infrastructure x1 fiction x6 wealth x8 duke x4 poverty x15 concussions x20 flocks x3 masks x3 diamonds x1 bubble x6 armageddon x28 recession x5 brown-fat x2 reflexivity x1 soros x3 Vivek x2 mediumismedicine x39 yield-curve x1 hearing-aids x2 supplements x1 desantis x1 florida x1 busted-medicine x2 supply-chain x1 death x28 hospice x1 dhc x2 gluten x3 duration x1 advertising x87 immigration x6 restaurants x1 unemployment x2 mortgage x2 wfh x3 bankruptcy x2 banks x1 modernity x12 tinnitus x8 baseball x1 sports x17 time x30 Yale x26 soccer x2 2008 x1 China x10 SSRI x18 blood-pressure x12 breath x9 elites x2 MAGA x2 addiction x89 blame x6 metaphors x24 california x10 coaching x3 cars x15 shortage x1 cteph x1 oxygen x2 pulmonary-embolism x19 trauma x2 whichworksbest x9 mobile x37 guns x4 paleopsychiatry x68 nocebo x2 placebo x36 self-experimentation x1 paris x6 schizophrenia x20 grief x3 learning x30 fMRI x33 focus x21 mind-body x17 mindfulness x10 SEO x4 diffusion x1 twiangulate x6 virtual x12 postpandemic x2 hrv x14 investing x16 keynes x1 jobs x17 overextrapolation x1 email x9 ALS x1 microbiome x72 community x57 love x18 collusion x1 housing x3 origin-story x6 start-ups x58 improv x17 magic x7 homeshoring x1 investment x1 repression x1 twins x1 civil-war x2 epigenetics x27 artifacts x2 optimism x2 self-image x20 oximeter x3 wearables x33 contagion x7 facebook x47 hysteria x1 Ukraine x7 ripples x2 meditation x48 pain x24 nanoniche x5 self-publishing x27 democracy x7 bullshit x1 carlson x2 authoritarianism x1 woke x2 friends x27 nose x4 autobiography x2 education x47 comedy x13 movies x14 1491 x1 clovis x1 eyes x12 deconstruction x9 goals x12 greenbrier x59 advice x2 secretword x1 collaboration x36 diversity x8 teams x5 hiring x1 practice x7 talent x1 metabolism x12 hte x21 science-is-dead x3 prefrontal-cortex x8 rtms x1 hyperbole x4 propofil x1 creativity x40 vision x22 hive-mind x11 murmuration x1 circadian x84 time-restricted-eating x6 bluelight x7 resting-heart-rate x7 Dont-use-mouthwash-after-running x2 peanuts x2 sunlight x69 central-europe x23 neanderthals x2 trust x11 sunk-costs x2 neurons x109 hsp90 x1 withdrawal x5 second-order-effects x1 unintended-consequences x4 censorship x7 lobbying x4 science-worship x1 inequality x54 insulin x22 conversation x24 coupling x3 engram x3 risk x12 evolution x16 panpsychist x5 synapses x12 t-cells x10 KOL x1 confidence x6 pricing x28 workation x1 presence x2 wisdom x5 anxiety x56 czechoslovakia x2 vaculik x2 tau x1 foucault x1 blood-thinners x1 group-think x7 vitamin-b-12 x1 UV x10 darwin x3 histamine x3 serotonin x20 cognitive-bias x4 heuristic x1 havel x8 rfe x1 vitamin-k x1 bogus-studies x8 language x49 maps x40 divorce x5 influence x6 prague x1 truth x1 deprescribing x1 polypharma x4 gamification x1 obesity x8 EKG x3 immortality x10 perception x6 purpose x3 cortisol x12 dogs x9 bass x6 ohio x4 emotion x17 digiceuticals x53 cerebral-cortex x4 consciousness x33 thalamus x2 luck x4 meritocracy x5 mimicry x1 nicotinamide x1 complexity x18 zoom x2 college x10 HDL x1 leadership x10 reviews x8 commuting x5 hypnosis x4 normal x1 voice x15 nutrition x3 bayes x1 local x11 newspapers x28 idioms x1 moderna x1 boredom x2 dreams x10 happiness x25 mice x8 competition x5 peers x17 simulation x1 mushrooms x1 fractals x7 power-law x2 glia x5 antibiotics x11 fear x10 methylation x3 density x1 italy x7 spotify x1 texas x1 IQ x21 gwas x2 naps x5 acentricity x2 capital-riot x1 work x11 moon x3 qanon x11 paranoia x9 Los-Angeles x3 arrowheads x1 center-vs-edges x1 gamestop x1 rationality x5 knee x1 twitches x1 status x5 abstraction x11 animals x11 money x13 mentoring x2 sex x4 mood x22 bipolar x11 lithium x8 apixaban x2 bitcoin x6 movement x3 fitbit x25 churchill x1 bias x19 bio-sensors x4 wearable x7 biocentrism x2 bots x11 library x4 randomness x7 dogma x2 novelty x3 rhythm x11 waves x10 motivation x38 zen x5 meat x3 agency x8 neurotypes x2 conspiracies x17 puzzle x5 slack x2 clinical-trials x5 plasticity x24 lean x2 architecture x10 cancel-culture x2 oxytocin x3 apps x28 tracking x3 privacy x14 privilege x2 stimulants x47 subjectivity x7 TV x10 blogs x37 machine-learning x4 epidemiology x1 black-swans x4 ecosystems x1 poker x2 conflict-of-interest x3 23andme x19 Gpld1 x1 CBT x20 robots x12 theranostics x17 albumin x1 blockchain x1 chemical-imbalance x2 taleb x1 telemedicine x3 law x14 railroads x1 witch-hunts x1 taxes x9 class x11 game-theory x1 police x15 genius x1 solitude x3 econ x59 end-times x10 booksellers x7 podcasting x5 photography x5 fakes x3 probability x2 dosage x2 middleages x2 kidney x2 salt x3 Israel x6 IgE x1 productivity x8 clusters x1 billionaires x1 2020 x1

spam x2 cleveland x1 c-diff x1 cherrypicking x1 methionine x1 payola x5 LCHF x1 budapest x5 40-Hz x2 demographics x5 midwest x5 design x33 tribalism x1 ehr x5 orphan-diseases x1 marfa x1 benzos x9 epic x1 dexcom x1 NIH x1 RCTs x8 cold-war x1 spying x3 parenting x22 bones x1 quantified-self x6 empathy x13 Great-to-do-business-with-you x1 contrarian x5 ecg x1 bun x1 malpractice x18 mucus x1 uber x1 bmj x1 block-that-metaphor x8 criticality x2 billing x1 bdnf x8 asthma x1 open-source x5 out-of-network x1 big-data x40 p-value x1 silent-sam x2 the-south x11 growth x5 mirror-neurons x7 infection x11 fiber x3 cvs x1 health-apps x6 generics x2 tolerance x1 caffeine x7 glutamate x6 prozac x2 smart-api x1 alexa x4 hope x1 metrics x1 fossil x3 fail x19 confounding x6 weird x1 lateral-septum x1 snapshots x1 dronabinal x2 chronic x1 CSA x1 calories x7 chess x4 dendrites x3 uniqueness x1 deterministic x1 omnigenics x1 clothing x6 turicibactor x1 paradigm-shift x2 organoids x1 gambling x7 christakis x5 UX x9 iga x2 social-shopping x6 nano-health x2 weightloss x15 anti-enlightenment x12 confirmation-bias x3 cbd x3 adventure x5 compsci x4 nasa x2 gamma-oscillations x4 dunning-kruger x6 mrsa x1 open-science x2 noise x4 homeostasis x3 fitness x16 straw-horses x1 dentate-gyrus x1 qs x2 thurston-howell-iii x1 hertz x2 joy x2 sales x17 telomeres x7 eeg x5 whole-grain x1 ending x3 hindsight x2 agnotology x1 fragmentation x3 uniforms x1 schema x4 polygenic x1 hand-written x3 walking x19 wellness x3 bio x4 aspirin x4 crp x1 dtc-health x1 simplify x9 life x49 dentists x2 vicious-circle x6 injury x6 shoes x4 sods-law x1 relapse x1 auctions x1 biofeedback x2 corpus-callosum x1 global-warming x3 here-we-go-again x1 cingulate-cortex x3 autism x3 garlic x1 jokes x24 laughter x3 dtc-gt x3 biomarkers x2 lab-on-a-chip x2 apple x29 pathways x1 omega-3 x1 vr x27 family x12 DMT x1 square-peg x1 gadgets x3 neighbor-effects x2 PTSD x11 mitochondria x6 autophagy x1 exponential x1 yeast x1 health-care-desert x1 training x12 addi x1 ritalin x2 life-logging x9 prisoners-dilemma x2 free-radicals x1 hypothalmus x3 belief x3 radio x4 reality x2 health-coach x2 Renaissance x4 GABA x7 causality x9 vagus x8 big-bro x3 lyme x3 bell-curve x1 510k x1 body-language x9 capitalism x3 caudate-nucleus x2 phrenology x1 covington x1 press x12 hipaa x1 xarelto x2 all-of-us x1 phosphate x1 dsm x6 netflix x2 touch x5 left-handed x2 analytics x6 categories x2 mission-creep x1 subconscious x2 india x1 identity x8 avoidance x3 denial x1 pans x5 lateral-orbitofrontal-cortex x1 symphony-not-soup x1 anger x3 loving-kindness x2 altitude x1 lungs x1 innovators-dilema x17 testosterone x1 default-network x1 avant-garde x1 Optimization x4 grandcanyon x1 hiking x1 self-fulfilling-prophecy x1 theta x1 libertarians x5 welch x1 COMT x2 avatars x2 generalizations x1 glutamine x1 nudges x1 cerebellum x7 psilocybin x4 hematology x1 wine x5 astrocytes x1 Chrdl1 x1 pop-ups x1 putin x4 panic-attacks x1 right-vagal-nerve x1 caring x2 HPA x2 loss x7 9-11 x2 naltrexone x1 aristocracy x2 lenin x2 Marx x6 new-york x8 vietnam x3 gratitude x5 vacation x1 fgf21 x1 war-on-drugs x8 civil-rights x9 statues x1 zero-sum x1 green x3 trees x5 extinction x3 breakfast x1 glycogen x1 trf x3 prosthetics x1 pessimism x1 leaderboards x3 nitric-oxide x1 customers x8 arthritis x3 barefoot x8 judaism x3 names x6 ego x6 yoga x3 adenosine x1 siblings x1 CNS x1 macrophages x1 kindle x1 SXSW x4 yes-and x1 wiring x1 DBS x4 strategy x11 chronotherapy x3 pr x2 clock x1 positivism x1 scale x3 tunable-leds x1 forgiveness x2 tablets x3 AACAP x1 listening x5 acupuncture x1 order x4 tb x1 noradrenline x1 speakersbureaus x4 biederman x5 courage x2 enlightenment x6 gyrification x1 lilly x1 chocolate x1 DHEA x1 jetlag x2 NIMH x1 LTP x1 mono x1 encephalitis x1 NMDA x1 ambiguity x1 peripheral x5 pivot x2 web x9 shooters x1 headaches x2 circular-reasoning x1 stem x1 anti-oxidents x1 malls x1 retailing x1 totalitarian x1 heller x1 subliminal x2 tools x15 dance x3 parallax x1 programmatic x12 branded-content x2 subscription x6 temperature x1 KGB x4 quacks x1 centaur x2 gould x1 frats x3 fog x1 syndrome x3 floating x1 swimming x3 platforms x4 fashion x10 jazz x1 cognitive-dissonance x1 stairs x3 compromise x4 energy x8 native-advertising x11 flow x1 salad x1 3d x4 orbit x2 space x6 rumination x3 neurofeedback x1 famous-last-words x3 metacognition x1 moscow x1 automation x7 autonomy x4 grammar x4 smile x2 gawker x45 gossip x6 weather x2 d4 x1 Hollywood x25 stalin x1 profanity x1 compound-interest x2 Freud x3 editing x6 ultra x8 Enterprise-Funds x1 PH x1 beer x5 hops x2 blog x6 suburbia x5 Hemingway x3 annotation x9 malware x1 CAMP x1 hypertension x1 tuberculosis x1 sad x4 thyroid x1 online-medicine x1 hypocracy x3 feedback x6 shibboleths x7 GAO x1 framingham x1 mantras x4 GIFs x3 marathon x3 bookstores x8 preventive-medicine x1 FOXO3 x1 sauna x2 LOL x35 offices x3 rubegoldberg x3 whiteboards x3 GLO1 x1 ACL x3 impact x1 vitamins x3 alienation x3 cms x8 Wapo x8 limbic x1 Pills-no-better-than-pushups x1 daily x1 Bannon x2 arbitrage x4 guilt x1 OCD x2 impulse x2 19thcentury x1 quick-fixes x1 ACA x2 chance x1 destiny x2 expats x1 biography x9 labor x4 cloud x2 benchmarks x3 crowdsourcing x8 obama x2 calendar x4 mormon x1 elephants x1 tea-party x6 irony x13 nostalgia x5 charity x8 millennials x2 rhetoric x18 UWS x1 resilience x1 dichotomy x1 VO2 x1 acting x5 quality-of-life x1 paradox x6 clinton x4 secrecy x8 trends x3 sarick x1 pride x3 Bach x2 theater x4 endorphins x1 rosemary x1 logistics x1 islam x1 golf x1 adrenaline x1 npr x1 SCOTUS x5 rules x1 linked-in x1 desegregation x6 audiences x3 mindreading x20 diffabilities x2 chickens x1 biz-models x16 discovery x6 serendipity x19 dolphins x2 ocean x2 migration x2 walmart x2 commodification x4 hypocrisy x8 yahoo x8 globalization x1 etiquette x2 anonymous x3 2016 x1 vectors x1 transparency x3 MIT x1 meta x16 gluts x6 tononi x2 curation x5 colorado x1 WTF x2 boondoggle x3 greenwald x2 venn-diagram x1 stockholm-syndrom x3 carr x14 earthquakes x3 facts x1 nixon x1 nyt x3 infographics x2 trolls x2 water x5 south x2 runwme x3 memes x2 GLBT x2 tesla x1 racewithme x12 sanity x3 runwithme x16 non-sequitors x1 Klan x1 Canada x1 drought x1 rationing x1 hacks x2 samizdat x2 book-tours x3 nicknotned x1 SUXORZ x7 fact-checking x2 ncaa x1 run-wither x1 mlk x1 rfk x1 viewability x1 api x1 crowd-sourcing x1 race-wither x1 metta x7 ISBN x1 asia x1 racewme x1 durham x5 freemium x3 bezos x21 surp x1 headlines x5 e-books x50 bloomberg x3 homepage x1 pq-praise x1 collecting x3 GTD x3 70s x1 memex x2 hubris x4 satire x1 cussing x1 odd x2 buzzfeed x4 PETA x1 repercussions x3 switzerland x1 data-follies x4 radical-chic x1 camelot x1 CPMs x1 slow-burn x1 iteration x3 vonnegut x1 apartheid x2 popularity x2 solar x1 signal x3 stream x4 WASPs x1 fracking x4 HDC x1 wikipedia x2 opacity x1 unknowing x3 linkalicous x1 bill-murray x1 cost-benefit x1 youth x1 milky-way x1 e-text x1 thin-skins x1 ancien-regime x1 mobsters x1 dixie x1 bedbugs x1 hashtags x2 weddings x1 moguls x2 geo x2 wandering x1 elasticity x1 chat x1 folksonomy x1 pinterest x2 yiddish x1 loop x1 middlebrow x1 20th-century x1 transience x1 content-sales x3 scams x2 kickstarter x1 mash-up x3 taglines x2 forking x3 peak-ads x3 pacino x1 DFW x1 portland x1 tool x3 b2b x1 cartoons x1 iron-curtain x1 16 x1 Hillary x1 Chromebook x1 mavericks x1 smb x1 penance x1 South-Africa x1 sherlock-holmes x1 Zap x2 niche-dsp x1 simonschuster x1 Maigret x1 audiobooks x1 ARPANET x1 jesus x1 stooges x1 oxymoron x3 revenge x1 curiosity x1 FUBAR x4 apprenticeship x1 didion x1 popova x3 hummingbird x2 blank-page x2 henry-blodget x3 bookmarks x2 hypocricy x2 FMCG x1 rand-paul x1 utopia x1 90s x1 displacement x1 assange x2 propaganda x1 oratory x1 PBS x1 TED x1 bricks x1 murdoch x1 quality x1 seventies x1 clive-thompson x1 asymmetry x1 lists x3 aol x1 huffpo x1 elegant x1 foursquare x1 medium x3 Tina-Brown x1 state-budgets x1 First-Amendment x3 recruiting x1 emergent x1 TDCS x1 klout x1 NSA x6 snowden x4 dematerialization x1 half-baked x1 boomers x1 pogue x3 turn-around x1 winer x1 naive x1 triumphalism x1 population x1 poitras x2 1984 x1 Orwell x1 geeks x1 cannibalization x1 salmon x1 hmm x1 malaprops x1 comments x1 dumb x1 aphasia x0 deme x0 diary x0 garmin x0 lolly x0 yhoo x0