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OSA 2x macular degeneration

According to him, "one theory is that the intermittent nighttime hypoxia caused by OSA leads to oxidative stress and inflammation, which can damage the retina and contribute to AMD. There's also evidence that OSA is linked to thinner choroids -- similar to what we see in AMD -- which might reduce blood flow to the outer retina."

Melatonin Use Tied to Decreased Risk of Age-Related Macular Degeneration | MedPage Today

Among propensity-matched patients ages 50 and older, melatonin use was associated with a reduced risk of developing AMD (risk ratio [RR] 0.42, 95% CI 0.28-0.62), reported Rishi P. Singh, MD, of Cole Eye Institute at the Cleveland Clinic, and colleagues in JAMA Ophthalmology opens in a new tab or window .