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Reduced Body Flexibility Is Associated With Poor Survival in Middle‐Aged Men and Women: A Prospective Cohort Study
To the best of our knowledge, this is the first cohort study to show that a reduced level of body flexibility—as assessed by the Flexindex, a composite score of maximal passive ROM of 20 movements in seven major joints—is related to higher mortality in a large middle- aged cohort of men and women. By analyzing death rates according Flexindex's data distribution, a consistent pattern emerged among middle- aged men and women, indicat- ing a gradual and inverse relationship between Flexindex and both natural and non- COVID- 19 mortality during an average follow- up of nearly 13 years. The association was most pronounced at the extremes of the Flexindex score distribution [death rate%]—men: [P91–99] 7.8% versus [P1–10] 21.2% and women: [P91–99] 2.0% versus [P1–10] 15.4%.—and remained significant when further sequentially ad- justed for age, BMI and health status.Introducing Working From Anywhere | HR Blog
A flexible working culture is built on trust, communication, collaboration, and connection and acknowledging that we’re all individuals, with different needs and rituals gives us the right frame of mind to let go of a few chosen truths and instead find what’s right for our business and our people. We have considered labour law, tax and insurance readiness for our workforce to be ‘working from anywhere’ – whether that’s working from home, in a café, hotel lounge or a co-working space. And, not forgetting the investment required to make sure the safety and growth of our people. Part of our DNA has always been controlled chaos. So, in the spirit of this, we’re trying this out knowing that there are likely to be some adjustments to make along the way. By experimenting and unlocking all talent we also enable diversity and inclusion, and making new jobs and markets available.
Meanwhile, in times of doubt, take inspiration in one last distinction of the teen brain—a final key to both its clumsiness and its remarkable adaptability. This is the prolonged plasticity of those late-developing frontal areas as they slowly mature. As noted earlier, these areas are the last to lay down the fatty myelin insulation—the brain's white matter—that speeds transmission. And at first glance this seems like bad news: If we need these areas for the complex task of entering the world, why aren't they running at full speed when the challenges are most daunting?
The answer is that speed comes at the price of flexibility. While a myelin coating greatly accelerates an axon's bandwidth, it also inhibits the growth of new branches from the axon. According to Douglas Fields, an NIH neuroscientist who has spent years studying myelin, "This makes the period when a brain area lays down myelin a sort of crucial period of learning—the wiring is getting upgraded, but once that's done, it's harder to change."