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Inflammation might be the root of preventable disease | Harvard Magazine
He is the physician-scientist who first demonstrated that a molecule called C-reactive protein (CRP), easily measured by a simple and now ubiquitous blood test, could be used like a thermometer to take the temperature of a patient’s inflammation. Elevated CRP, he discovered years ago, predicts future cardiovascular events, including heart attacks. Although nobody knows what it does biologically, this marker is downstream from IL-1beta, and thus provides a reliable yardstick of that pro-inflammatory pathway’s level of activation.