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Mechanisms of tissue and cell-type specificity in heritable traits and diseases | Nature Reviews Genetics

Hundreds of heritable traits and diseases that are caused by germline aberrations in ubiquitously expressed genes manifest in a remarkably limited number of cell types and tissues across the body. Unravelling mechanisms that govern their tissue-specific manifestations is critical for our understanding of disease aetiologies and may direct efforts to develop treatments.

#hte #Great-to-do-business-with-you - nature.com

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